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KMID : 0357119800020010017
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Korean Journal of Immunology
1980 Volume.2 No. 1 p.17 ~ p.22
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Detection of Antibodies to Salmonella Typhi in the Bile of Immunized Rabbits
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李憲九/Lee, Hurn-Ku
河大有/Ha, Tai-You
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Abstract
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It is believed that the majority of intestinal immunoglobulins is derived from local synthesis by plasma cells in the lamina propria.
However, this study was attempt to investigate the possibility that a part of the intestinal immunoglobulins might be originated from biliary system.
Hillary secretion of rabbit antibodies against Salmonella typhi 0901 was studied by biliary surgery with T-tube.
About 0.4% of the serum antibodies was detected in bile juice and almost of them were imm unoglobulin M but IgG antibody was not detected in bile juice.
The biliary surgery performed in this experiment provides a good experimental model for the study of secretory immunoglobulins of biliary system.
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